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miSRA: search preprocessed public small-RNA data against your reference sequences (miRNA, tRNA, etc)
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miSRA description

miSRA is a database and webserver tool that allows fast and easy querying of uniformly preprocessed publicly available small RNA sequencing (miRNA-seq) datasets. miSRA can also generate expression profiles of miRNAs and other small RNAs using sRNAbench. The database currently contains over 130,000 preprocessed miRNA-seq data sets from over 900 species obtained from the Sequence Read Archive. Different types of input reference sequences are supported:
  • microRNAs: sRNAbench will be used for expression profiling of the user provided microRNAs within the user selected samples (SRX,ERX and DRX accessions).
  • Longer reference sequences: sRNAbench will align reads from the selected samples to these reference sequences providing expression matrixes and mapping frequency as a function of position
  • Short exact reference sequences: sRNAbench will be used in ‘spike-in’ mode, i.e. only exact matches will be reported.

How to start

To use miSRA you need SRA identifiers like SRX/ERX/DRX (experiment level) or SRP/ERP/DRP (study level). If you already have the IDs you want to analyse, you can go directly to any of the 'miSRA tools'. Alterativly, you can browse the database selecting the samples through a keyword search using miRNA Selector.